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Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer’s disease

6 Aug 2024

Abstract excerpt

Lewy body dementia (LBD), a class of disorders comprising Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), features substantial clinical and pathological overlap with Alzheimer's disease (AD). The identification of biomarkers unique to LBD pathophysiology could meaningfully advance its diagnosis, monitoring, and treatment. Using quantitative mass spectrometry (MS), we measured over 9,000...

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PMID: 39107789
DOI: 10.1186/s13024-024-00749-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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