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Article

The increased chromosomal DNA damage in patients with Familial Mediterranean Fever.

Biotechnic & histochemistry : official publication of the Biological Stain Commission - 1 Aug 2024

Kiraz Aslihan, Eciroglu Hamiyet, Altin-Celik Pınar, Donmez-Altuntas Hamiyet

Abstract excerpt

Familial Mediterranean Fever (FMF) is an inherited autoinflammatory disease. In this study, we aimed to assess chromosomal DNA damage and cell proliferation by using cytokinesis-block micronucleus cytome (CBMN-cyt) assay in the peripheral blood lymphocytes of untreated FMF patients carrying M694V and R202Q mutations, which are the most common MEFV gene mutations in Turkish society. The study included 20 untreated...

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Identifiers

PMID: 39092615
DOI: 10.1080/10520295.2024.2383960

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