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THE LYMPHOCYTE CYTOKINESIS-BLOCK MICRONUCLEUS CYTOME ASSAY AND ITS APPLICATION IN RADIATION BIODOSIMETRY

6 Jan 2010

Abstract excerpt

The cytokinesis-block micronucleus cytome (CBMN Cyt) assay is one of the best-validated methods for measuring chromosome damage in human lymphocytes. This paper describes the methodology, biology, and mechanisms underlying the application of this technique for biodosimetry following exposure to ionizing radiation. Apart from the measurement of micronuclei, it is also possible to measure other important biomarkers...

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PMID: 20065688
DOI: 10.1097/hp.0b013e3181b85044

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