Article
Epigenetic Alterations and an Increased Frequency of Micronuclei in Women with Fibromyalgia
1 Jan 2013
Abstract excerpt
Fibromyalgia (FM), characterized by chronic widespread pain, fatigue, and cognitive/mood disturbances, leads to reduced workplace productivity and increased healthcare expenses. To determine if acquired epigenetic/genetic changes are associated with FM, we compared the frequency of spontaneously occurring micronuclei (MN) and genome-wide methylation patterns in women with FM (n = 10) to those seen in comparably...
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