Article
Prevalence of FA-D2 rare complementation group of Fanconi anemia in Serbia.
Indian journal of pediatrics - 1 Mar 2014
Dragana Vujić, Sandra Petrović, Emilija Lazić, Miloš Kuzmanović, Andreja Leskovac, Ivana Joksić, Dragan Mićić, Ankica Jovanović, Zeljko Zečević, Marija Guć-Šćekić, Sanja Cirković, Gordana Joksić
Abstract excerpt
OBJECTIVE: To investigate genetic subtypes of inherited bone marrow failure syndrome Fanconi anemia (FA) in Sebia. FA-D2 subtype was found to be the most frequent genetic subtype among investigated FA patients; specific observations of FA-D2 phenotype are pointed out. METHODS: Several biological endpoints of FA cells in vitro such as radiation-induced level of lymphocyte micronuclei (radiosensitivity), base line...
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