Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ionizing radiation or mitomycin-induced micronuclei in lymphocytes of BRCA1 or BRCA2 mutation carriers.

Breast cancer research and treatment - 1 Jun 2011

Gutiérrez-Enríquez Sara, Ramón Y Cajal Teresa, Alonso Carmen, Corral Anna, Carrasco Pablo, Cornet Mónica, Sanz Judith, Ribas Montserrat, Baiget Montserrat, Diez Orland

Abstract excerpt

BRCA1 and BRCA2 genes are essential in preserving the integrity of genome, and it is not unambiguously clear whether the heterozygosity status may affect BRCA1 or BRCA2 functions. This may have implications for the clinical management of BRCA1 and BRCA2 mutation carriers both in breast cancer (BC) screening modality and in cancer treatment based on DNA-damaging or DNA-repair-inhibiting drugs. We investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Lymphocytes

Share to Micronuclei, Chromosome-Defective

Share to Mitomycin

Source

Identifiers

PMID: 20625817
DOI: 10.1007/s10549-010-1017-6

Genes

BRCA2
BRCA1
NPB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ionizing radiation or mitomycin-induced micronuclei in lymphocytes of BRCA1 or BRCA2 mutation carriers.PMID 20625817Read ↗

Role of micronucleus test in predicting breast cancer susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

Chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay.Semantic proximity Read ↗

Molecular contribution of BRCA1 and BRCA2 to genome instability in breast cancer patients: review of radiosensitivity assaysSemantic proximity Read ↗

Clinical application of micronucleus test: a case-control study on the prediction of breast cancer risk/susceptibility.Semantic proximity Read ↗

Radiosensitivity of peripheral blood lymphocytes obtained from patients with cancers of the breast, head and neck or cervix as determined with a micronucleus assay.Semantic proximity Read ↗

Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families.Semantic proximity Read ↗

Increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of bladder cancerSemantic proximity Read ↗

Chromosomal mutagen sensitivity associated with mutations in BRCA genes.Semantic proximity Read ↗

Radiosensitivity in breast cancer assessed by the Comet and micronucleus assaysSemantic proximity Read ↗

Diagnosis of Fanconi Anaemia by ionising radiation- or mitomycin C-induced micronuclei.Semantic proximity Read ↗

A 24-color metaphase-based radiation assay discriminates heterozygous BRCA2 mutation carriers from controls by chromosomal radiosensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.