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Genome instability in peripheral blood lymphocytes of patients with heart failure and reduced ejection fraction

4 Feb 2023

Abstract excerpt

Heart failure (HF) is a complex clinical condition characterized by functional and structural defects of the myocardium, but genetic and environmental factors are considered to play an important role in the development of the disease. In the present study, we investigated the genome instability (DNA and chromosomal damage) in patients with heart failure with reduced ejection fraction (HFrEF) ≤40% and its...

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PMID: 36738247
DOI: 10.1093/mutage/gead002

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