Article
KRAS Mutation Subtypes and Their Association with Other Driver Mutations in Oncogenic Pathways.
Cells - 19 Jul 2024
Mondal Koushik, Posa Mahesh Kumar, Shenoy Revathi P, Roychoudhury Susanta
Abstract excerpt
The KRAS mutation stands out as one of the most influential oncogenic mutations, which directly regulates the hallmark features of cancer and interacts with other cancer-causing driver mutations. However, there remains a lack of precise information on their cooccurrence with mutated variants of KRAS and any correlations between KRAS and other driver mutations. To enquire about this issue, we delved into...
Topics
- Humans
- Mutation
- Proto-Oncogene Proteins p21(ras)
- Signal Transduction
- Neoplasms
- Oncogenes
- Carcinogenesis
- Class I Phosphatidylinositol 3-Kinases