Article
Impact of DNA repair polymorphisms on DNA instability biomarkers induced by lead (Pb) in workers exposed to the metal.
Chemosphere - 1 Sept 2023
Nunes Emilene Arusievicz, Silva Heliton Camargo da, Duarte Nathália de Assis Aguilar, de Lima Lindiane Eloisa, Maraslis Flora Troina, Araújo Marília Ladeira de, Pedron Tatiana, Neves Lange Camila, Freire Bruna Moreira, Matias Andreza Cândido, Batista Bruno Lemos, Barcelos Gustavo Rafael Mazzaron
Abstract excerpt
Although the mechanisms of Pb-induced genotoxicity are well established, a wide individual's variation response is seen in biomarkers related to Pb toxicity, despite similar levels of metal exposure. This may be related to intrinsic variations, such as genetic polymorphisms; moreover, very little is known about the impact of genetic variations related to DNA repair system on DNA instability induced by Pb. In this...
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