Increased micronucleus frequencies in reticulocytes of children exposed to industrial pollution: oxidative stress and the OGG1 S326C polymorphism.

doi:10.1016/j.mrgentox.2020.503170

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Increased micronucleus frequencies in reticulocytes of children exposed to industrial pollution: oxidative stress and the OGG1 S326C polymorphism.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 May 2020

Montero-Montoya Regina D, López-Vargas Rocío, Méndez-Serrano Alejandra, Galicia-Alonso Isaías, García-Vargas Guadalupe, Serrano-García Luis, Beltrán-Portugal Rosa, Rosado-Zaidi Samuel, Albores-Medina Arnulfo, Oropeza-Hernández Luis, Hernández-Cadena Leticia, Mercado-Calderón Francisco, Alvarado-Toledo Esmeralda, Herrera-Morales Selene, Arellano-Aguilar Omar

Abstract excerpt

We examined possible early-effect biomarkers and polymorphisms of susceptibility in primary school children living near the Atoyac River in central México, which receives waste from multiple industries. We observed a significant increase in micronucleated reticulocytes associated with the oxidative stress index (OSI) and the OGG1 GG (S326C) genotype, and a significant decrease of reticulocytes carrying the...

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PMID: 32522350
DOI: 10.1016/j.mrgentox.2020.503170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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