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Application of Fluorescence in Situ Hybridization to Detect MYCN Amplification on Paraffin-embedded Tissue Sections of Neuroblastoma - Single Institute Study.

2020-10-26

Abstract excerpt

<title>Abstract</title> <p>BackgroundNeuroblastoma is the most common extracranial solid tumour in children. Amplification of the <italic>MYCN</italic> gene was observed in approximately 20-30% of tumours. It is strongly correlated with advanced stage of disease, rapid tumour progression, resistant to chemotherapy and poor outcome independent of patient age and stage of advanced disease. Amplification of the <ita...

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Literature Corpus work
7fb5b1ff-45ae-5577-b0fb-496af2d5ead1
DOI
10.21203/rs.3.rs-95672/v1
Open publication

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Application of Fluorescence in Situ Hybridization to Detect MYCN Amplification on Paraffin-embedded Tissue Sections of Neuroblastoma - Single Institute Study.DOI 10.21203/rs.3.rs-95672/v1
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