Article
Shifts in receptors during submergence of an encephalitic arbovirus.
Nature - 1 Aug 2024
Li Wanyu, Plante Jessica A, Lin ChieYu, Basu Himanish, Plung Jesse S, Fan Xiaoyi, Boeckers Joshua M, Oros Jessica, Buck Tierra K, Anekal Praju V, Hanson Wesley A, Varnum Haley, Wells Adrienne, Mann Colin J, Tjang Laurentia V, Yang Pan, Reyna Rachel A, Mitchell Brooke M, Shinde Divya P, Walker Jordyn L, Choi So Yoen, Brusic Vesna, Llopis Paula Montero, Weaver Scott C, Umemori Hisashi, Chiu Isaac M, Plante Kenneth S, Abraham Jonathan
Abstract excerpt
Western equine encephalitis virus (WEEV) is an arthropod-borne virus (arbovirus) that frequently caused major outbreaks of encephalitis in humans and horses in the early twentieth century, but the frequency of outbreaks has since decreased markedly, and strains of this alphavirus isolated in the past two decades are less virulent in mammals than strains isolated in the 1930s and 1940s1-3. The basis for this...
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