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Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

28 Mar 2024

Abstract excerpt

Climate change and population densities accelerated transmission of highly pathogenic viruses to humans, including the Crimean-Congo haemorrhagic fever virus (CCHFV). Here we report that the Low Density Lipoprotein Receptor (LDLR) is a critical receptor for CCHFV cell entry, playing a vital role in CCHFV infection in cell culture and blood vessel organoids. The interaction between CCHFV and LDLR is highly...

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PMID: 38548922
DOI: 10.1038/s41564-024-01672-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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