Article
Association between a single-nucleotide polymorphism of the angiotensin-converting enzyme gene and susceptibility to systemic lupus erythematosus in the Hainanese population of China.
International journal of immunogenetics - 1 Oct 2024
Zhang Qi, Zhuang Yanping, Zhang Xuan, Lin Guiling, Wu Huitao, He Ziman, Wang Zhe, Xu Wenlu, Yin Xiyu, Su Linglan, Jia Xiaokang, Gong Aimin
Abstract excerpt
The angiotensin-converting enzyme (ACE) gene plays a significant role in regulating immune responses and inflammatory processes, thus impacting the susceptibility to systemic lupus erythematosus (SLE). Understanding how single-nucleotide polymorphisms (SNPs) within the ACE gene contribute to the genetic susceptibility to SLE is essential for comprehending the disease's aetiology. Therefore, exploring this...
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