Article
Association of interleukin 22 gene polymorphisms and serum IL-22 level with risk of systemic lupus erythematosus in a Chinese population.
Clinical and experimental immunology - 1 Aug 2018
Wang R, Zeng Y-L, Qin H-M, Lu Y-L, Huang H-T, Lei M, Tan T, Huang Y-Y, Luo H-C, Lan Y, Wei Y-S
Abstract excerpt
The aim of this study was to investigate the association between the single-nucleotide polymorphisms (SNPs) of the interleukin 22 (IL-22) gene and systemic lupus erythematosus (SLE) in a Chinese population. Three IL-22 SNPs (rs2227485, rs2227513 and rs2227491) were genotyped using SNaPshot SNP genotyping assays and identified by sequencing in 314 SLE patients and 411 healthy controls. The IL-22 level of serum was...
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