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Article

Leucine rich α2 glycoprotein 1 derived from malignant pleural mesothelioma cells facilitates macrophage M2 phenotypes.

Experimental lung research - 1 Jan 2024

Wang Dandan, Pei Wenjing, Liu Yanfei, Mo Rongliang, Li Xinru, Gu Wenhui, Su Yi, Ye Jing, Xu Jiegou, Zhao Dahai

Abstract excerpt

Background: Macrophages constitute the main part of infiltrating immune cells in Malignant pleural mesothelioma (MPM) and abnormally high ratios of M2 macrophages are present in both pleural effusion and tissue samples of MPM patients. Whether MPM cells affect formation of M2 macrophages is poorly understood. In this study, we focused on identification of MPM-cells-derived soluble factors with M2-promoting...

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Identifiers

PMID: 39033404
DOI: 10.1080/01902148.2024.2380988

Genes

LRG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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