Article
Proteomic characterization of four subtypes of M2 macrophages derived from human THP-1 cells.
Journal of Zhejiang University. Science. B - 15 May 2022
Li Pengfei, Ma Chen, Li Jing, You Shanshan, Dang Liuyi, Wu Jingyu, Hao Zhifang, Li Jun, Zhi Yuan, Chen Lin, Sun Shisheng
Abstract excerpt
Macrophages are widely distributed immune cells that contribute to tissue homeostasis. Human THP-1 cells have been widely used in various macrophage-associated studies, especially those involving pro-inflammatory M1 and anti-inflammatory M2 phenotypes. However, the molecular characterization of four M2 subtypes (M2a, M2b, M2c, and M2d) derived from THP-1 has not been fully investigated. In this study, we...
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