Article
Performance comparison of two next-generation sequencing panels to detect actionable mutations in cell-free DNA in cancer patients.
Clinical chemistry and laboratory medicine - 28 Jul 2020
Macías Mónica, Cañada-Higueras Eva, Alegre Estibaliz, Bielsa Arancha, Gracia Javier, Patiño-García Ana, Ferrer-Costa Roser, Sendino Teresa, Andueza María P, Mateos Beatriz, Rodríguez Javier, Corral Jesús, Gúrpide Alfonso, Lopez-Picazo José M, Perez-Gracia Jose L, Gil-Bazo Ignacio, Alkorta-Aranburu Gorka, González Álvaro
Abstract excerpt
Background Genomic alterations studies in cell-free DNA (cfDNA) have increasing clinical use in oncology. Next-generation sequencing (NGS) technology provides the most complete mutational analysis, but nowadays limited data are available related to the comparison of results reported by different platforms. Here we compare two NGS panels for cfDNA: Oncomine™ Pan-Cancer Cell-Free Assay (Thermo Fisher Scientific),...
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