Article
Genetic distance and ancestry proportion modify the association between maternal genetic risk score of type 2 diabetes and fetal growth.
Human genomics - 19 Jul 2024
Habtewold Tesfa Dejenie, Wijesiriwardhana Prabhavi, Biedrzycki Richard J, Tekola-Ayele Fasil
Abstract excerpt
BACKGROUND: Maternal genetic risk of type 2 diabetes (T2D) has been associated with fetal growth, but the influence of genetic ancestry is not yet fully understood. We aimed to investigate the influence of genetic distance (GD) and genetic ancestry proportion (GAP) on the association of maternal genetic risk score of T2D (GRST2D) with fetal weight and birthweight. METHODS: Multi-ancestral pregnant women...
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