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Article

Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth.

Human genetics - 1 Jul 2021

Tekola-Ayele Fasil, Ouidir Marion, Shrestha Deepika, Workalemahu Tsegaselassie, Rahman Mohammad L, Mendola Pauline, Grantz Katherine L, Hinkle Stefanie N, Wu Jing, Zhang Cuilin

Abstract excerpt

Fetal growth is an important determinant of cardiometabolic disease risk during childhood and adulthood. The genetic architecture of fetal growth remains largely understudied in ancestrally diverse populations. We conducted genome-wide admixture mapping scan and analysis of genetic ancestry among Hispanic American, African American, European American, and Asian American pregnant women to identify genetic loci...

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Identifiers

PMID: 33590300
DOI: 10.1007/s00439-021-02265-4
PMCID: PMC8197736

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