Distinction between the effects of parental and fetal genomes on fetal growth.

doi:10.1038/s41588-021-00896-x

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Distinction between the effects of parental and fetal genomes on fetal growth.

Nature genetics - 1 Aug 2021

Juliusdottir Thorhildur, Steinthorsdottir Valgerdur, Stefansdottir Lilja, Sveinbjornsson Gardar, Ivarsdottir Erna V, Thorolfsdottir Rosa B, Sigurdsson Jon K, Tragante Vinicius, Hjorleifsson Kristjan E, Helgadottir Anna, Frigge Michael L, Thorgeirsson Gudmundur, Benediktsson Rafn, Sigurdsson Emil L, Arnar David O, Steingrimsdottir Thora, Jonsdottir Ingileif, Holm Hilma, Gudbjartsson Daniel F, Thorleifsson Gudmar, Thorsteinsdottir Unnur, Stefansson Kari

Abstract excerpt

Birth weight is a common measure of fetal growth that is associated with a range of health outcomes. It is directly affected by the fetal genome and indirectly by the maternal genome. We performed genome-wide association studies on birth weight in the genomes of the child and parents and further analyzed birth length and ponderal index, yielding a total of 243 fetal growth variants. We clustered those variants...

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PMID: 34282336
DOI: 10.1038/s41588-021-00896-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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