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Generalisability of Maternal Genetic Risk Score for Birth Weight Across Racial Identity and Ancestry: A Secondary Analysis of a Prospective Cohort Study.

BJOG : an international journal of obstetrics and gynaecology - 1 Mar 2026

Tristani-Firouzi Bita, Pappas Lisa, Joseph Merry, Zeinomar Maryam, Debbink Michelle P, Mims Joseph, Guerrero Rafael, Moore Barry, Silver Robert M, Workalemahu Tsegaselassie, Haas David, Steller Jonathan G, Saade George, Blue Nathan R

Abstract excerpt

OBJECTIVE: Maternal genotypes may be useful to customise foetal growth assessment, but generalisability across diverse racial and ancestral groups remains uncertain. We assessed the generalisability of a genetic risk score for birth weight (GRSBW), derived from participants of predominantly European ancestry, within a diverse U.S. COHORT: DESIGN: Secondary analysis of a prospective observational cohort of...

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PMID: 41320779
DOI: 10.1111/1471-0528.70088
PMCID: PMC12884248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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