Article
Genetic risk score for prediction of newborn adiposity and large-for-gestational-age birth.
The Journal of clinical endocrinology and metabolism - 1 Nov 2014
Chawla Reeti, Badon Sylvia E, Rangarajan Janani, Reisetter Anna C, Armstrong Loren L, Lowe Lynn P, Urbanek Margrit, Metzger Boyd E, Hayes M Geoffrey, Scholtens Denise M, Lowe William L
Abstract excerpt
CONTEXT: Macrosomic infants are at increased risk for adverse metabolic outcomes. Improving prediction of large-for-gestational-age (LGA) birth may help prevent these outcomes. OBJECTIVE: This study sought to determine whether genes associated with obesity-related traits in adults are associated with newborn size, and whether a genetic risk score (GRS) predicts LGA birth. SETTING AND DESIGN: Single nucleotide...
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