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Article

Organ-on-Chip Approaches for Intestinal 3D In Vitro Modeling

25 Aug 2021

Abstract excerpt

The intestinal epithelium has one of the highest turnover rates in the human body, which is supported by intestinal stem cells. Culture models of intestinal physiology have been evolving to incorporate different tissue and microenvironmental elements. However, these models also display gaps that limit their similarity with native conditions. Microfluidics technology arose from the application of microfabrication...

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PMID: 34454168
DOI: 10.1016/j.jcmgh.2021.08.015

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