Article
Paired comparison of the analytical performance between the Oncomine™ Comprehensive Assay v3 and whole-exome sequencing of ovarian cancer tissue.
Molecular biology reports - 17 Jul 2024
Lopacinska-Jørgensen Joanna, Vestergaard Lau K, Schejbel Lone, Høgdall Claus K, Poulsen Tim Svenstrup, Høgdall Estrid V
Abstract excerpt
BACKGROUND: Next-generation sequencing (NGS) has been implemented in clinical oncology as a personalized medicine tool to identify targetable genetic alterations and to guide treatment decisions. However, the optimal NGS test strategy and target genes for clinical use are still being discussed. The aim was to compare the performance of the Oncomine™ Comprehensive Assay v3 (OCAv3) (targeted gene panel) and...
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