Article
Whole-exome sequencing reveals rare genetic variations in ovarian granulosa cell tumor.
Bosnian journal of basic medical sciences - 1 Jun 2022
Kim Seungyeon, Kim Songmi, Mun Seyoung, Kwak Yongsik, Suh Kwang-Sun, Choi Song-Yi, Han Kyudong
Abstract excerpt
Ovarian granulosa cell tumor (OGCT) is a rare ovarian tumor that accounts for about 2-5% of all ovarian tumors. Despite the low grade of ovarian tumors, high and late recurrences are common in OGCT patients. Even though this tumor usually occurs in adult women with high estrogen levels, the cause of OGCT is still unknown. To screen genetic variants associated with OGCT, we collected normal and matched-tumor...
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