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Article

Whole-exome mutational landscape and molecular marker study in mucinous and clear cell ovarian cancer cell lines 3AO and ES2.

BMC cancer - 6 Apr 2023

Li Jianxiong, Liang Huaguo, Xiao Wentao, Wei Peng, Chen Hongmei, Chen Zexin, Yang Ruihui, Jiang Huan, Zhang Yongli

Abstract excerpt

BACKGROUND: Ovarian cancer is one of the most lethal cancers in women because it is often diagnosed at an advanced stage. The molecular markers investigated thus far have been unsatisfactory. METHODS: We performed whole-exome sequencing on the human ovarian cancer cell lines 3AO and ES2 and the normal ovarian epithelial cell line IOSE-80. Molecular markers of ovarian cancer were screened from shared mutation...

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Identifiers

PMID: 37024829
DOI: 10.1186/s12885-023-10791-9
PMCID: PMC10080944

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