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Article

Integrated in-silico design and in vivo validation of multi-epitope vaccines for norovirus

27 May 2025

Abstract excerpt

BACKGROUND: Norovirus (NoVs) is a foodborne pathogen that causes acute gastroenteritis. The diversity of its principal antigenic protein poses a significant challenge to vaccine development and the prevention of large-scale outbreaks globally. Currently, no licensed vaccines against norovirus have been approved. METHODS: We developed a novel pipeline that integrates multiple bioinformatics tools to design...

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PMID: 40426240
DOI: 10.1186/s12985-025-02796-6

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