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Associations between polyunsaturated fatty acid concentrations and Parkinson’s disease: A two-sample Mendelian randomization study

22 Feb 2023

Abstract excerpt

Introduction Observational studies demonstrated controversial effect of polyunsaturated fatty acids (PUFAs) on Parkinson’s disease (PD) with limited causality evidence. Randomized control trials showed possible improvement in PD symptoms with PUFA supplement but had small study population and limited intervention time. Methods A two-sample Mendelian randomization was designed to evaluate the causal relevance...

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PMID: 36909950
DOI: 10.3389/fnagi.2023.1123239

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