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Article

Quantitative trait locus mapping in placenta: A comparative study of chorionic villus and birth placenta.

HGG advances - 10 Oct 2024

Dieckmann Linda, Lahti-Pulkkinen Marius, Cruceanu Cristiana, Räikkönen Katri, Binder Elisabeth B, Czamara Darina

Abstract excerpt

The placenta, a pivotal player in the prenatal environment, holds crucial insights into early developmental pathways and future health outcomes. In this study, we explored genetic molecular regulation in chorionic villus samples (CVS) from the first trimester and placenta tissue at birth. We assessed quantitative trait locus (QTL) mapping on DNA methylation and gene expression data in a Finnish cohort of 574...

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Identifiers

PMID: 38993113
DOI: 10.1016/j.xhgg.2024.100326
PMCID: PMC11365441

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