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Genome-wide DNA methylation study in human placenta identifies novel loci associated with maternal smoking during pregnancy

1 Sept 2016

Abstract excerpt

BACKGROUND: We conducted an epigenome-wide association study (EWAS) of DNA methylation in placenta in relation to maternal tobacco smoking during pregnancy and examined whether smoking-induced changes lead to low birthweight. METHODS: DNA methylation in placenta was measured using the Illumina HumanMethylation450 BeadChip in 179 participants from the INfancia y Medio Ambiente (INMA) birth cohort. Methylation...

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PMID: 27591263
DOI: 10.1093/ije/dyw196

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