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Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysis

10 Apr 2024

Abstract excerpt

Biological sex is a key variable influencing many physiological systems. Disease prevalence as well as treatment success can be modified by sex. Differences emerge already early in life and include pregnancy complications and adverse birth outcomes. The placenta is a critical organ for fetal development and shows sex-based differences in the expression of hormones and cytokines. Epigenetic regulation, such as DNA...

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PMID: 38600394
DOI: 10.1007/s00018-024-05208-0

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