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DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases

3 Jun 2020

Abstract excerpt

BACKGROUND: Birthweight marks an important milestone of health across the lifespan, including cardiometabolic disease risk in later life. The placenta, a transient organ at the maternal-fetal interface, regulates fetal growth. Identifying genetic loci where DNA methylation in placenta is associated with birthweight can unravel genomic pathways that are dysregulated in aberrant fetal growth and cardiometabolic...

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PMID: 32493484
DOI: 10.1186/s13148-020-00873-x

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