Article
Sex-differentiated placental methylation and gene expression regulation has implications for neonatal traits and adult diseases
1 May 2025
Abstract excerpt
Sex differences in physiological and disease traits are pervasive and begin during early development, but the genetic architecture of these differences is largely unknown. Here, we leverage the human placenta, a transient organ during pregnancy critical to fetal development, to investigate the impact of sex in the regulatory landscape of placental autosomal methylome and transcriptome, and its relevance to health...
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