Article
SExual Epigenetic Dimorphism in The Human Placenta: Implications for Susceptibility During The Prenatal Period
17 Feb 2017
Abstract excerpt
AIM: Sex-based differences in response to adverse prenatal environments and infant outcomes have been observed, yet the underlying mechanisms for this are unclear. The placental epigenome may be a driver of these differences. METHODS: Placental DNA methylation was assessed at more than 480,000 CpG sites from male and female infants enrolled in the extremely low gestational age newborns cohort (ELGAN) and...
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