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Article

A gain of function mutation in PITX2c gene linked to atrial fibrillation alters mitochondrial function and membrane excitability.

Vascular pharmacology - 1 Jun 2024

Benzoni Patrizia, Da Dalt Lorenzo, Cospito Alessandro, Popolizio Vera, Giannetti Federica, Ruberti Cristina, Baruscotti Mirko, Bucchi Annalisa, Norata Giuseppe Danilo, Barbuti Andrea

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Share to Atrial Fibrillation
Share to Gain of Function Mutation
Share to Homeobox Protein PITX2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Membrane Potential, Mitochondrial

Share to Mitochondria, Heart

Share to Myocytes, Cardiac

Share to Transcription Factors

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Identifiers

PMID: 38985600
DOI: 10.1016/j.vph.2024.107298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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A gain of function mutation in PITX2c gene linked to atrial fibrillation alters mitochondrial function and membrane excitability.PMID 38985600Read ↗

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PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene ExpressionSemantic proximity Read ↗

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In Silico Assessment of Genetic Variation in PITX2 Reveals the Molecular Mechanisms of Calcium-Mediated Cellular Triggered Activity in Atrial Fibrillation.Semantic proximity Read ↗

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In silico investigation of the mechanisms underlying atrial fibrillation due to impaired Pitx2.Semantic proximity Read ↗

Understanding PITX2-dependent Atrial Fibrillation Mechanisms through Computational ModelsSemantic proximity Read ↗

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