Article
Partitioning the Genomic Components of Behavioral Disinhibition and Substance Use (Disorder) Using Genomic Structural Equation Modeling.
Behavior genetics - 1 Sept 2024
Horwitz Tanya B, Zorina-Lichtenwalter Katerina, Gustavson Daniel E, Grotzinger Andrew D, Stallings Michael C
Abstract excerpt
Externalizing behaviors encompass manifestations of risk-taking, self-regulation, aggression, sensation-/reward-seeking, and impulsivity. Externalizing research often includes substance use (SUB), substance use disorder (SUD), and other (non-SUB/SUD) "behavioral disinhibition" (BD) traits. Genome-wide and twin research have pointed to overlapping genetic architecture within and across SUB, SUD, and BD. We created...
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