Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating the causal association between obesity and risk of hepatocellular carcinoma and underlying mechanisms

8 Jul 2024

Abstract excerpt

Obesity is a global health concern and independent risk factor for cancers including hepatocellular carcinoma (HCC). However, evidence on the causal links between obesity and HCC is limited and inconclusive. This study aimed to investigate the causal relationship between obesity-related traits and HCC risk and explore underlying mechanisms using bioinformatics approaches. Two-sample Mendelian randomization...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer-related molecular mechanisms research
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38977823
DOI: 10.1038/s41598-024-66414-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating the causal association between obesity and risk of hepatocellular carcinoma and underlying mechanismsPMID 38977823Read ↗

Bidirectional Mendelian randomization analysis of the causal association between obesity and hepatocellular carcinoma in a European population.Semantic proximity Read ↗

Overweight/obesity-related transcriptomic signature as a correlate of clinical outcome, immune microenvironment, and treatment response in hepatocellular carcinomaSemantic proximity Read ↗

ESR1 regulates the obesity and metabolism-differential gene MMAA to inhibit the occurrence and development of hepatocellular carcinomaSemantic proximity Read ↗

Body fatness associations with cancer: evidence from recent epidemiological studies and future directionsSemantic proximity Read ↗

The association between metabolic syndrome and hepatocellular carcinoma risk: a Mendelian randomization studySemantic proximity Read ↗

Exploring Hepatocellular Carcinoma Etiology through Multi-omics BioinformaticsSemantic proximity Read ↗

ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular CarcinomaSemantic proximity Read ↗

Genetic insights of waist-to-height ratio on the risk of steatotic and advanced liver diseases: genome-wide association study and polygenic risk score-based analyses.Semantic proximity Read ↗

Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma.Semantic proximity Read ↗

A Multivariable Mendelian Randomization Analysis Disentangling The Causal Relations Between Abdominal Obesity, Non-Alcoholic Fatty Liver Disease and Cardiometabolic DiseasesSemantic proximity Read ↗

Visceral and ectopic fat are more predictively associated with primary liver cancer than overall obesity from genetic sights: A Mendelian randomization study.Semantic proximity Read ↗

Associations between modifiable risk factors and hepatocellular carcinoma: a trans-ancestry Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.