Article
The expression of MIR125B transcripts and bone phenotypes in Mir125b2-deficient mice.
PloS one - 1 Jan 2024
Ogasawara Tomohiro, Ito Shota, Ogashira Shintaro, Hoshino Tomonori, Sotomaru Yusuke, Yoshiko Yuji, Tanimoto Kotaro
Abstract excerpt
MIR125B, particularly its 5p strand, is apparently involved in multiple cellular processes, including osteoblastogenesis and osteoclastogenesis. Given that MIR125B is transcribed from the loci Mir125b1 and Mir125b2, three mature transcripts (MIR125B-5p, MIR125B1-3p, and MIR125B2-3p) are generated (MIR125B-5p is common to both); however, their expression profiles and roles in the bones remain poorly understood....
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