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Article

Symptomatic Heart Failure and Clonal Hematopoiesis-Related Mutations in Patients With Acute Myeloid Leukemia.

The American journal of cardiology - 1 Sept 2024

Kang Yu, Lefebvre Benedicte, Pamies Ingrid Marti, Gill Saar I, Doucette Abigail G, Denduluri Srinivas, Smith Amanda M, McCurdy Shannon, Luger Selina, Carver Joseph, Scherrer-Crosbie Marielle

Abstract excerpt

Clonal hematopoiesis of indeterminate potential (CHIP) is a common risk factor for hematologic malignancies and cardiovascular diseases. This study aimed to investigate the association between CHIP-related mutations and symptomatic heart failure (HF) in patients diagnosed with acute myeloid leukemia (AML). A total of 563 patients with newly diagnosed AML who underwent DNA sequencing of bone marrow before...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38972534
DOI: 10.1016/j.amjcard.2024.06.033
PMCID: PMC11330721

Genes

DNMT3A
ASXL1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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