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Article

Clonal Hematopoiesis of Indeterminate Potential and Long-term Outcomes in Heart Transplantation.

Journal of cardiac failure - 1 Feb 2025

Simitsis Panagiotis, Nohria Anju, Kelleher Jane, Boulet Jacinthe, Wanderley Mauro R B, Natarajan Pradeep, Libby Peter, Mehra Mandeep R

Abstract excerpt

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) mutations, a trait of aging, has been associated with the progression of cardiovascular disease and the development of malignancy. Uncertainty prevails regarding a robust association between CHIP and heart-transplantation (HT) outcomes. OBJECTIVES: To determine the prevalence of CHIP mutations in HT and their association with long-term outcomes,...

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Source

Identifiers

PMID: 38885783
DOI: 10.1016/j.cardfail.2024.05.011

Genes

DNMT3A
PPM1D
SF3B1
TET2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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