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Article

No causal relationship between serum urate and neurodegenerative diseases: A Mendelian randomization study.

Experimental gerontology - 1 Sept 2024

Wang Min, Tang Zhiquan

Abstract excerpt

OBJECTIVE: Observational studies have shown that increased serum urate is associated with a lower risk of neurodegenerative diseases (NDs), but the causality remains unclear. We employed a two-sample Mendelian randomization (MR) approach to assess the causal relationship between serum urate and four common subtypes of NDs, including Parkinson's disease (PD), Alzheimer's disease (AD), amyotrophic lateral sclerosis...

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Source

Identifiers

PMID: 38955238
DOI: 10.1016/j.exger.2024.112503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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