Article
Renal function and neurodegenerative diseases : a two-sample Mendelian randomization study.
Neurological research - 1 May 2023
Liu Xue, Ou Ya-Nan, Ma Ya-Hui, Huang Liang-Yu, Zhang Wei, Tan Lan
Abstract excerpt
BACKGROUND: Observational studies showed renal function had associations with Alzheimer's disease (AD), Parkinson's disease (PD), Lewy body dementia (LBD) and multiple sclerosis (MS). However, it is unknown whether these associations are causal. METHODS: We use a two-sample Mendelian randomization (MR) analysis to investigate causal relationships between renal function and 6 neurodegenerative diseases (NDDs): AD...
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