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Article

Genetic Variations Affect Chemotherapy Outcomes: A Role of the Spindle-assembly Checkpoint.

Indian journal of public health - 1 Apr 2024

Sarkar Sinjini, Pal Ranita, Choudhury Trisha, Vernekar Manisha, Nath Partha, Nasare Vilas D

Abstract excerpt

Cancer patients suffer from complicated chemotoxicity. Pharmacogenomics can help stratify patients by predicting their response to treatment and susceptibility toward severe side effects. The spindle-assembly checkpoint (SAC) is an important pathway that is activated by platinum and taxane compounds and plays a crucial role in their cytotoxic activity. This study investigated a SAC component, Budding Uninhibited...

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Identifiers

PMID: 38953826
DOI: 10.4103/ijph.ijph_809_23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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