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Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies

23 Feb 2024

Abstract excerpt

The identification of clinically-relevant biomarkers is of upmost importance for the management of cancer, from diagnosis to treatment choices. We performed a pan-cancer analysis of the mitotic checkpoint budding uninhibited by benzimidazole 1 gene BUB1, in the attempt to ascertain its diagnostic and prognostic values, specifically in the context of drug response. BUB1 was found to be overexpressed in the...

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PMID: 38396175
DOI: 10.1038/s41598-024-55080-y

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