Article
Invasive Assessment of Coronary Artery Disease in Clonal Hematopoiesis of Indeterminate Potential.
Circulation. Genomic and precision medicine - 1 Aug 2024
Heimlich J Brett, Raddatz Michael A, Wells John, Vlasschaert Caitlyn, Olson Sydney, Threadcraft Marcus, Foster Kristoff, Boateng Emmanuel, Umbarger Kelsey, Su Yan Ru, Roden Dan M, Barker Colin M, Bick Alexander G
Abstract excerpt
BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) occurs due to acquired mutations in bone marrow progenitor cells. CHIP confers a 2-fold risk of atherosclerotic cardiovascular disease. However, there are limited data regarding specific cardiovascular phenotypes. The purpose of this study was to define the coronary artery disease phenotype of the CHIP population-based on coronary angiography....
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