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Article

Clonal hematopoiesis of indeterminate potential and heart disease: What every internist needs to know.

Cleveland Clinic journal of medicine - 1 May 2026

Oren Ohad, Singh Abhay, Carraway Hetty E, Laffin Luke J, Nissen Steven E

Abstract excerpt

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition defined by somatic mutations in hematopoietic stem cells that result in clonal expansion, without overt hematologic malignancy. It is now recognized as a potent risk factor for atherosclerotic cardiovascular disease, with emerging associations across a broader spectrum of cardiovascular phenotypes, including myocarditis,...

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PMID: 42067232
DOI: 10.3949/ccjm.93a.26003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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