Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FoxG1/BNIP3 axis promotes mitophagy and blunts cisplatin resistance in osteosarcoma

26 Jun 2024

Abstract excerpt

Cisplatin (CDDP) is a commonly used chemotherapeutic for osteosarcoma (OS) patients, and drug resistance remains as a major hurdle to undermine the treatment outcome. Here, we investigated the potential involvement of FoxG1 and BNIP3 in CDDP resistance of OS cells. FoxG1 and BNIP3 expression levels were detected in the CDDP-sensitive and CDDP-resistant OS tumors and cell lines. Mitophagy was observed through...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine and Purinergic Signaling
Share to Autophagy in Disease and Therapy
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38932521
DOI: 10.1111/cas.16242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FoxG1/BNIP3 axis promotes mitophagy and blunts cisplatin resistance in osteosarcomaPMID 38932521Read ↗

Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagySemantic proximity Read ↗

Bayesian‐optimized deep learning for identifying essential genes of mitophagy and fostering therapies to combat drug resistance in human cancersSemantic proximity Read ↗

Mitophagy in the mechanisms of treatment resistance in solid tumorsSemantic proximity Read ↗

GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcomaSemantic proximity Read ↗

Exosome-mediated miR-144-3p promotes ferroptosis to inhibit osteosarcoma proliferation, migration, and invasion through regulating ZEB1Semantic proximity Read ↗

Dual Role of Mitophagy in Cancer Drug ResistanceSemantic proximity Read ↗

Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasisSemantic proximity Read ↗

PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKTSemantic proximity Read ↗

Optineurin enhances the chemoresistance by activating mitophagy in acute myeloid leukemia with NPM1 mutation.Semantic proximity Read ↗

Theaflavin‐3,3′‐Digallate Plays a ROS‐Mediated Dual Role in Ferroptosis and Apoptosis via the MAPK Pathway in Human Osteosarcoma Cell Lines and XenograftsSemantic proximity Read ↗

FOXO3a‐dependent Parkin regulates the development of gastric cancer by targeting ATP‐binding cassette transporter E1Semantic proximity Read ↗

Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.