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Article

Dual Role of Mitophagy in Cancer Drug Resistance

20 Jan 2018

Abstract excerpt

The effectiveness of chemotherapy is largely limited by drug resistance. In the past few decades, modulation of anticancer drug resistance plays little role in benefit of clinical outcomes due to complex drug resistance mechanisms. Mitophagy, an important mitochondrial quality control system, selectively degrades excessive or damaged mitochondria by autophagy. Accumulating reports are suggesting that...

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PMID: 29374684
DOI: 10.21873/anticanres.12266

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