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Extracellular vesicles or free circulating DNA: where to search for BRAF and cKIT mutations?

Nanomedicine : nanotechnology, biology, and medicine - 1 Apr 2018

Klump Jennifer, Phillipp Ulrike, Follo Marie, Eremin Anna, Lehmann Hannes, Nestel Sigrun, von Bubnoff Nikolas, Nazarenko Irina

Abstract excerpt

Clinical evidence in oncology argues for the advantages of performing molecular analysis of blood biomarkers to provide information about systemic changes and tumor heterogeneity. Whereas the diagnostic value of cell-free circulating DNA (fcDNA) has successfully been demonstrated in several studies, DNA enclosed in extracellular vesicles (EV) has only recently been described, and its potential diagnostic value is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Identifiers

PMID: 29288729
DOI: 10.1016/j.nano.2017.12.009

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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